Description of Study

The aim of the research study is to examine the acute effects of a single-day, split dosing protocol (3x10 grams) of creatine monohydrate on cognitive performance in healthy adults.

Location
Exercise and Performance Nutrition Laboratory (Fieldhouse 126)
209 S Kingshighway St
Saint Charles, MO 63301

Number of Visits
3

Time Commitment
Visits 1-3: 30-45 minutes

Points of Contact
Wyatt McLaughlin
epnl@lindenwood.edu

Research Sample Needed

• 50-60 healthy men and women

Inclusion Criteria

• Between 18 and 50 years old.
• In good general health with no unmanaged chronic medical conditions (e.g., hypertension, cardiovascular disease, or neurological disorders).
• No creatine or cognitive-enhancing supplements (e.g., nootropics) within the past 30 days.
• Not currently taking medications that impact cognitive function, sleep, or physiological measures (e.g., sedative, stimulants, antidepressants).
• Must be available to attend all testing visits over 4 consecutive days.
• Must agree to maintain their usual sleep and physical activity routines throughout the study.
• Able to consume the supplement at home (or outside the lab) and arrive at the lab within 150-170 minutes post-ingestion.
• Must report regular sleep patterns (e.g., 6-9 hours per night).
• No history of shift work or frequent travel across time zones within the past 14 days.

Exclusion Criteria

• Diagnosed with or receiving treatment for cardiovascular disease, neurological disorders, or psychiatric conditions.
• Diagnosed with sleep disorders (e.g., insomnia, sleep apnea).
• Pregnant, breastfeeding, or planning to become pregnant during the study period.
• Currently using medications known to affect cognitive function, sleep, or physiological outcomes (e.g., sedatives, stimulants, antidepressants).
• Taken nootropics or other cognitive-enhancing supplements (e.g., modafinil, racetams) within the past 30 days.
• Inability to maintain consistent daily routines during the study period (frequent time zone changes, shift work).
• Unwilling or unable to attend all study visits or complete required assessments.
• Non-compliance with the supplementation or data collection protocols.

Are You Eligible?

• Complete initial screening form for this study.

Information provided here reflects current IRB approval for this research. However, this information may be subject to change and updated accordingly.